← Biochemistry (BIOCHEM)

Hardest courses in Biochemistry

Plan ahead for courses where students have earned lower grades.

Lowest historical GPA first. At least 100 letter grades over the five years through the selected term. Grades reflect past outcomes, not workload or a guaranteed result.

Find your fit

15 courses

Ranked courses have at least 100 recorded letter grades.

Biology of Viruses covers animal virology at the molecular level, focusing on virus structure, replication/lifecycle, pathogenesis, and prevention.

Offering recorded · Spring 2027 · Sources

Past student reviews · Andrew Mehle

The course was described as tough, with detailed lecture slides that could feel overwhelming, though students advised focusing on general concepts rather than every tiny detail.

historical GPA · grades

Spring 2023–Spring 2026

Covers biosynthesis, signal transduction, nucleic acid metabolism, protein synthesis, and molecular/cellular biology.

Offering recorded · Spring 2027 · Sources

Past student reviews · Sebastian York Bednarek

Exams rely heavily on irrelevant details, requiring students to memorize specific enzyme and cofactor names. Success demands consistent study habits rather than last-minute cramming.

historical GPA · grades

Fall 2022–Spring 2026

Survey of Biochemistry explores chemical properties of biomolecules, metabolism, and DNA processes, linking them to disease, drug design, and gene therapy; it does not prepare students for advanced biochemistry or med/vet admission.

Offering recorded · Spring 2027 · Sources

Past student reviews · Paul Friesen

Homework was graded on completion, though points were deducted for brief answers to questions.

historical GPA · grades

Spring 2023–Spring 2026

General Biochemistry I covers the chemistry of biological materials, intermediary metabolism, and protein structure.

Offering recorded · Spring 2027 · Sources

Past student reviews · Timothy Grant

Lectures alone were insufficient for mastering the course content, so students needed to supplement their learning by reading the assigned textbook.

historical GPA · grades

Fall 2022–Spring 2026

EUKARYOTIC MOLECULAR BIOLOGY focuses on basic molecular mechanisms regulating DNA, RNA, and protein metabolism in eukaryotes, including a thesis research project.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Spring 2023–Spring 2026

Nutritional Biochemistry and Metabolism covers biochemical and physiological fundamentals of nutrition, including protein, fat, carbohydrate, energy, minerals, and vitamins in nutrition and metabolism.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026

Introduction to Biochemistry covers the chemistry, nutrition, and metabolism of biological systems, emphasizing biomolecular structures, genetic information processes, and central metabolic pathways.

Offering recorded · Spring 2027 · Sources

Past student reviews · Mario Pennella

Students reported that Mario Pennella’s section was dense and required a lot of time to understand the material well enough to succeed on the multiple-choice exam.

historical GPA · grades

Fall 2022–Spring 2026

Biochemical Methods introduces modern biochemical laboratory techniques and literature, featuring student seminar presentations that parallel lab experiments.

Offering recorded · Spring 2027 · Sources

Past student reviews · Lynne Prost

One student found the lectures and exams easy, though they described the lab component as difficult and annoying, with presentations accounting for 15% of the grade.

historical GPA · grades

Fall 2022–Spring 2026

First-year seminar introducing the discipline of biochemistry, the UW Biochemistry Department, faculty research projects, university resources, and career options for students with a biochemistry background.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026

Seminar on computation and informatics in biology and medicine.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026

Introduction to molecular life mechanisms and evolutionary diversity, exploring current topics like gene editing, genomics, and biotechnology to evaluate scientific claims.

Offering recorded · Spring 2027 · Sources

Past student reviews · Mario Pennella

Homework required about 30 minutes per week, and exams tested material presented in class.

historical GPA · grades

Fall 2022–Spring 2026

Graduate course covering selected topics in contemporary macromolecular or biophysical chemistry, focusing on discussing current topics of active interest in molecular biophysics.

Offering recorded · Spring 2027 · Sources

Past student reviews · Alessandro Senes

The course was rated as moderately difficult, with clear expectations set by the instructor.

historical GPA · grades

Fall 2022–Spring 2026

Advanced Topics covers specialized subjects of current interest in biochemistry.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026

Seminar where Biotechnology Training Program trainees present research and internship work for critical review and discussion of industrial biotechnology applications.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026

Independent Study involves research work under the direct guidance of a Biochemistry faculty member.

Offering recorded · Spring 2027 · Sources

historical GPA · grades

Fall 2022–Spring 2026