HUMAN GENETICS

GENETICS 605

The use of genetics in medicine has experienced significant growth over the past 50 years, identifying risk genes, and devising diagnostic tests and therapies based on this knowledge for specific clinical disorders such as cystic fibrosis, achondroplasia, and Retts syndrome. MDs and biomedical scientists from UW Hospital and Clinics, the School of Medicine and Public Health, and other UW units will present lectures in this field followed by question-answers sessions. Other class sessions will be devoted to student presentations and open discussion of research literature.

MDGENET 911

Genetics and genomics are rapidly evolving fields. In modern clinical care settings, clinicians will be exposed to genetic and genomic data, including that brought by patients, and knowing how to read genetic and genomic data is increasingly necessary in clinical practice. Genetics and genomics in a clinical setting spans a wide range of topics including diagnosis and treatment of genetic diseases. Familiarity with clinical genetic analysis, and the genetic approaches used in basic science, helps medical students better understand genetic disease background. Learn how to bridge basic concepts of human genetics and clinical genetics (actual diseases). Emphases will include research into human genetic diseases, including designing genetic testing, using model organisms and/or cell culture systems, and the development of genetic testing technologies.

GENETICS/MDGENET/POPHLTH 636

Provides an introduction to public health genomics through a review of fundamental principles of genetics, the use of genetic information in clinical and research settings, and its implications for disease management and prevention, and health promotion. Explores policies that guide public health and discusses current ethical, legal, and social implications of these policies.

PATH 949

The genome impacts human health and disease from the moment of conception throughout growth, development, and aging. This course offers a comprehensive overview of clinical laboratory testing in the fields of medical genetics and public health. Topics include how genetic testing is integrated into patient care, including prenatal genetics, newborn screening, genetic testing in children and adults, and oncology genetics. Students will develop a strong foundational knowledge of basic genetics principles, identify indications for genetic testing, interpret population screening results and the implications for public health, assess the utility of diagnostic testing, and recognize the limitations of genetic testing and clinical laboratory medicine. It is anticipated that students will incorporate these concepts, knowledge, experiences, and evidence in their future clinical practice.

GENETICS 335

The ability to sequence genomes rapidly has transformed our understanding of the evolution of species and human history, our approaches to improve health and medicine, as well as how we tackle global environmental challenges, and increasingly impacts our modern world. Explore the interdisciplinary connections between genetics- and genomics-based research and important current questions related to ethics, history, and public policy.