GENETICS THROUGH THE LIFE CYCLE

GENETICS/MDGENET 565

Principles, problems, and methods of modern human genetics. Focuses on how researchers discover the genetics of diseases and how those discoveries are used to improve clinical practice. Surveys aspects of (i) the molecular function of the human genome, (ii) the basic principles of human genetics including statistical genetics, quantitative genetics, and genomic variation in human populations, (iii) the genetics of rare disorders and common diseases, and genomic analysis approaches, including genome-wide association studies and sequencing, and (iv) how genetics are used in medicine and discussions covering ethical considerations of human genomic data.

MDGENET 911

Genetics and genomics are rapidly evolving fields. In modern clinical care settings, clinicians will be exposed to genetic and genomic data, including that brought by patients, and knowing how to read genetic and genomic data is increasingly necessary in clinical practice. Genetics and genomics in a clinical setting spans a wide range of topics including diagnosis and treatment of genetic diseases. Familiarity with clinical genetic analysis, and the genetic approaches used in basic science, helps medical students better understand genetic disease background. Learn how to bridge basic concepts of human genetics and clinical genetics (actual diseases). Emphases will include research into human genetic diseases, including designing genetic testing, using model organisms and/or cell culture systems, and the development of genetic testing technologies.

GENETICS/MDGENET/POPHLTH 636

Provides an introduction to public health genomics through a review of fundamental principles of genetics, the use of genetic information in clinical and research settings, and its implications for disease management and prevention, and health promotion. Explores policies that guide public health and discusses current ethical, legal, and social implications of these policies.

GENECSLR 740

Introduction to clinical laboratory genetics with a particular focus on the relevance of human cytogenetics and molecular genetics to the practice of medical genetics. Covers the fundamental principles of human cytogenetic and molecular genetics including human chromosome structure, function, cytogenetic and molecular nomenclature, and current clinical laboratory testing methods relevant to medical genetic professionals. Apply cytogenetic and molecular genetic understanding to clinical scenarios to help diagnosis and manage individuals with genetic disease.

MEDSC-M 773

Focuses on molecular, genetic, embryologic, hormonal, anatomical and physiological factors that govern fertility, cell growth, fetal development, and pregnancy as well as the congenital anomalies that can occur when those processes are aberrant. Encompasses the full life-cycle spectrum including childhood growth and development, young adulthood/puberty, issues affecting adolescents and young adults, genetic basis of human disease, reproductive health, menopause, aging, unregulated cell growth (cancer) and end of life issues. Significant content from other competency domains, or "longitudinal threads", such as public health, advocacy, ethics, patient care/communication and clinical skills.