GENOMES IN A MODERN WORLD

GENETICS/MDGENET 565

Principles, problems, and methods of modern human genetics. Focuses on how researchers discover the genetics of diseases and how those discoveries are used to improve clinical practice. Surveys aspects of (i) the molecular function of the human genome, (ii) the basic principles of human genetics including statistical genetics, quantitative genetics, and genomic variation in human populations, (iii) the genetics of rare disorders and common diseases, and genomic analysis approaches, including genome-wide association studies and sequencing, and (iv) how genetics are used in medicine and discussions covering ethical considerations of human genomic data.

ANSCI 366

Genomics has revolutionized many fields of science, including animal breeding, plant breeding, physiology, microbiology, and human medicine. A basic overview of the latest concepts in genomics, including 3D genome organization, the importance of genome annotation, the use of genomic testing in plant and animal breeding, the potential of genomic prediction on human medicine, and the latest advances in omics integration.

GENETICS 234

The sequencing of genomes has transformed our understanding of the evolution of species and human history, our approaches to improve health and medicine, as well as how we tackle global environmental challenges. Explore the many ways in which the sequencing of genomes is revolutionizing our world, and dive into DNA from viral to human genomes. Understand how genomes are expressed, the impact on phenotype, as well as how it can change over time and in different conditions, are processes that are essential for life and the evolution of species.

ZOOLOGY 415

Covers a range of topics related to human genetics and evolution. Explores questions about what genetic differences between humans tell us about our species' evolutionary and demographic history, and conversely, how our history has shaped the genetic diversity of people living today. At a time of rapidly increasing ability to sequence huge numbers of genomes such questions play a central role in understanding how genetics impacts individuals' disease risks, how to interpret reported ancestry and family history from direct-to-consumer genotyping kits, and how genetics can (or importantly, cannot) inform descriptions of human diversity and concepts of race. Includes topics of diversity and inclusion in genomics studies, with a focus on the application and limits of results obtained from one group to our understanding of other groups.

GENETICS 548

Profound advances are now possible thanks to genomic data and analysis. Introduces the structure, function, and evolution of genomes. It also outlines the realized and prospective benefits of genomic technology for human health, agriculture, and conservation.