MOLECULAR AND CELLULAR MECHANISMS OF MEMORY

NEURODPT/NTP 640

Theory and application of methods in computational neuroscience across various levels of organization from single cells to global brain dynamics and cognition. Computational neuroscience is an approach to understanding the development and function of nervous systems in mechanistic terms at many different structural scales. Topics include biophysical properties of neurons and synapses, neural plasticity, sensory systems, neural circuits, whole brain analysis and modeling, and different views on brain function. Includes primers on relevant computational techniques (ICA, information theoretical approaches, dynamical systems) and a computational problem set. Starts with an introduction to MATLAB (used for problem sets).

NEURODPT/NTP 610

Study of original papers leading to an understanding of the molecular basis of electrical activity in neurons. Topics include voltage-sensitive currents, molecular biology of neuronal receptorrs, synaptic transmission and sensory transduction.

NTP 900

Critical review of selected topics in neurobiology.

PSYCH/ZOOLOGY 523

Basic mechanisms in cellular neurophysiology: electrophysiology and chemistry of nerve signals, mechanisms in integration, simple nervous pathways and their behavioral correlates.

ZOOLOGY 444

Provides an advanced understanding of cell biology as it relates to the nervous system. Covers the neuronal cytoskeleton, molecular motors and their cargos, the secretory system and how it functions in neurons, formation and maintenance of pre- and post-synaptic structures, neuronal organelles and their functions. Discussion of what is known about the disruptions to cell biology of neurons that contributes to neurodevelopmental and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, Charcot Marie Tooth Disease, Spinal Muscular Atrophy, and others.