MATHEMATICAL METHODS FOR SYSTEMS BIOLOGY

BMI/COMPSCI 775

Introduces networks as a powerful representation in many real-world domains including biology and biomedicine. Encompasses theory and applications of networks, also referred to as graphs, to study complex systems such as living organisms. Surveys the current literature on computational, graph-theoretic approaches that use network algorithms for biological modeling, analysis, interpretation, and discovery. Enables hands-on experience in network biology by implementing computational projects.

MM&I 760

An overview of methods used in quantitative systems biology, with a focus on biochemical systems relevant to the study of host-pathogen interactions, disease and microbial communities.

BME 556

Introduction to the experimental and mathematical modeling techniques used in systems biology through lectures and critical analyses of relevant publications with a primary focus on gene/protein networks and mammalian systems.

BME 780

Focuses on understanding the key methods and principles of quantitative biology through a close reading of the primary literature. Topics covered will include deterministic and stochastic methods for modeling cellular systems, techniques in systems and synthetic biology, image processing tools and image analysis for biology, data-driven network models, genomic approaches, single-molecule approaches, and key computational biology tools. This course is intended for graduate students from a variety of backgrounds who are interested in pursuing quantitative biology during their graduate studies.

BMOLCHEM 720

Covers following areas from historical to modern contexts: biochemistry of post-translational modification of proteins, model organisms, transcriptional switches, chromosome replication, and RNA in biological regulation.