We're still actively developing this site. If you encounter any issues, please report them! - Report an issue

MODELING NEURODEVELOPMENTAL DISEASE

ZOOLOGY 655
Course Description

Systematically explores current animal models of human diseases that affect the central nervous system. Topics will include birth defects that disrupt normal brain architecture (holoprosencephaly and neural tube closure defects), birth defects affecting the visual system, and postnatal disease, e.g. neurodegeneration and stroke.

Prerequisties
Satisfies

This course does not satisfy any prerequisites.

Credits

Not Reported

Offered

Not Reported

Grade Point Average
Not Reported

Could not calculate change

Completion Rate
Not Reported

Could not calculate change

A Rate
Not Reported

Could not calculate change

Class Size
Not Reported

No change from Historical

No data available

Instructors (2025 Fall)

Sorted by ratings from Rate My Professors

Similar Courses

DEVELOPMENTAL NEUROSCIENCE

NEURODPT/NTP/ZOOLOGY 765

Analysis of neural development with emphasis on experimental approaches. Combination of lectures and discussions of primary literature. Topics include neural induction, patterning, mechanisms of axon guidance, neural crest cell migration and differentiation, cortical development, and synapse formation and elimination.

NEUROBIOLOGY OF DISEASE

NEUROL 735

Overview of the major categories of human neurological and opthalmological disease to fundamental topics in neurobiology.

ANIMAL DEVELOPMENTAL GENETICS

GENETICS 627

Advanced genetics course focusing on genetic mechanisms of animal embryonic development, with particular emphasis on central molecular circuitries that control development and genetic analytical tools used to reveal them. Address topics including maternal and epigenetic inheritance, the egg-to-embryo transition, pattern formation, organogenesis, coordination of cellular and molecular mechanisms, and animal models of human congenital disorders.

MODELING HUMAN DISEASE IN ANIMALS

ONCOLOGY 745

Provides a background in the use of animals in the study of human disease and hands-on exposure to common techniques such as tissue collection and processing, surgeries, imaging, and other manipulations. Lectures by basic scientists and clinicians will provide background about each of the organ systems or diseases and the ethics of animal research. Prior to start of course, completion of online animal safety training. Instructions will be provided after enrollment.

NEURONAL CELL BIOLOGY IN HEALTH AND DISEASE

ZOOLOGY 444

Provides an advanced understanding of cell biology as it relates to the nervous system. Covers the neuronal cytoskeleton, molecular motors and their cargos, the secretory system and how it functions in neurons, formation and maintenance of pre- and post-synaptic structures, neuronal organelles and their functions. Discussion of what is known about the disruptions to cell biology of neurons that contributes to neurodevelopmental and neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, Charcot Marie Tooth Disease, Spinal Muscular Atrophy, and others.