NEUROGENETICS

GENETICS 627

Advanced genetics course focusing on genetic mechanisms of animal embryonic development, with particular emphasis on central molecular circuitries that control development and genetic analytical tools used to reveal them. Address topics including maternal and epigenetic inheritance, the egg-to-embryo transition, pattern formation, organogenesis, coordination of cellular and molecular mechanisms, and animal models of human congenital disorders.

NEUROL 735

Overview of the major categories of human neurological and opthalmological disease to fundamental topics in neurobiology.

GENETICS/MDGENET 707

A research-level analysis of the current status of the investigation of processes controlling differential gene activity and cellular behavior. The major emphasis is genetic. In successive years, the focus moves from the gene to the cell to the organism.

GENETICS/MDGENET 565

Principles, problems, and methods of modern human genetics. Focuses on how researchers discover the genetics of diseases and how those discoveries are used to improve clinical practice. Surveys aspects of (i) the molecular function of the human genome, (ii) the basic principles of human genetics including statistical genetics, quantitative genetics, and genomic variation in human populations, (iii) the genetics of rare disorders and common diseases, and genomic analysis approaches, including genome-wide association studies and sequencing, and (iv) how genetics are used in medicine and discussions covering ethical considerations of human genomic data.

GENETICS 568

Anatomy, physiology, histology and pathology of the central nervous system and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen preparation. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.