GENOMICS AND PROTEOMICS

ANSCI 366

Genomics has revolutionized many fields of science, including animal breeding, plant breeding, physiology, microbiology, and human medicine. A basic overview of the latest concepts in genomics, including 3D genome organization, the importance of genome annotation, the use of genomic testing in plant and animal breeding, the potential of genomic prediction on human medicine, and the latest advances in omics integration.

GENETICS 885

With the availability of genome sequences and high-throughput techniques, organismal physiology can now be examined on a global scale by monitoring the behavior of all genes or proteins in a single experiment. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course material will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proteomic screening methods, and protein-interaction network analysis. In addition to lecture time, the course includes computer lab where students get hands-on experience analyzing genomic and proteomic datasets. Students should have coursework in general statistics and intermediate or advanced genetics.

CHEM/GENETICS 626

Brings cutting-edge topics in the genomic sciences into the reach of those in chemistry, biology, engineering, computer science statistics fields. Enables biologically-oriented students to deal with advances in analytical science so that they may incorporate new genomic science concepts into their own scientific repertoires.

PATH 970

Advances in medicine are increasingly being driven by "big data" analyses, including proteomics, genomics, and metabolomics. Basic knowledge of how to analyze these datasets can allow one to generate and test hypotheses that have the potential to transform a field. In this course, students will conduct individual data mining expeditions using a collection of large proteomics and metabolomics data sets. Formulate hypotheses about the interrelationships of molecules and their potential relationship to health, disease, and biological phenotypes. Basic background instruction on "omics" methodologies, heritability studies, and analytical methods will be provided. Provides the basic knowledge to carry out future 'omics analyses; using scientific inquiry to potentially transform the practice of medicine.

CHEM 923

Cross-disciplinary exposure to cutting edge research in genomic sciences. Seminars presented by trainees and other scientists who study genomics using approaches based in chemistry, computer science, biostatistics, engineering and biological and biomedical sciences. Research objectives, findings and future directions are discussed.