BIOPHYSICAL SPECTROSCOPY

BME/CHEM/MEDPHYS 750

Covers several aspects of state-of-the-art biological and biophysical imaging with an emphasis on instrumentation, beginning with an overview of geometrical optics and optical and fluorescence microscopy. The bulk of the course will focus on advanced imaging techniques including nonlinear optical processes (multi-photon excitation, second harmonic generation, and stimulated Raman processes) and emerging super-resolution methods. Special emphasis will be given to current imaging literature and experimental design. Knowledge of physics-based optics [such asPHYSICS 202] strongly recommended.

CHEM 623

Current spectroscopic methods employed in chemical analysis with applications in atomic and molecular absorption spectroscopy, infrared and Raman vibrational spectroscopy, fluorescence and light scattering; lecture and laboratory projects.

CHEM 665

Equilibrium thermodynamics and chemical kinetics with emphasis on solution behavior and applications to biological macromolecules in solution. Focus on biological applications of physical chemistry.

BIOCHEM/CHEM 918

A combination of recent literature and original research presentations relating to the use of single molecule techniques in biochemistry including fluorescence microscopy, tethered particle motion, patch-clamping, cryo-electron microscopy, optical trapping, magnetic tweezers, and super resolution microscopy.

BIOCHEM/CHEM 872

Various selected topics in contemporary macromolecular or biophysical chemistry.