ENDOCRINOLOGY AND METABOLISM

NUTRSCI 625

Physiology, biochemistry and genetics of human obesity and diabetes. Critical review of current research on their etiology and treatment.

NUTRSCI 710

Fundamentals in human macronutrient metabolism and its role in health and disease. Biochemistry and physiology of macronutrient digestion, anabolism, and catabolism. Disorders of energy metabolism (obesity, type 1 and type 2 diabetes, starvation). Metabolic effects of fiber and the microbiota. Body composition and energy assessment. Taught in an online format using lectures, guided readings, and projects.

BIOCHEM/NUTRSCI 645

Examination of various physiological states and how they affect metabolic pathways. Discussion of a number of special topics related to the unique roles of various tissues and to metabolic pathways in disease states, including adipocyte biology, beta-cell biology, epigenetics, inflammation, and aging related diseases.

OBS&GYN 710

A broad grounding in reproductive endocrine physiology at the graduate level, with an emphasis on human and human reproductive health wherever possible. Encompasses an overview of fundamental concepts in endocrinology, the hypothalamic-pituitary axis, steroidogenesis, early embryonic development, pregnancy and maternal-fetal adaptations, and pathologies associated with endocrine disruption and dysregulation. Provides more focus on pathologic pregnancies because such pregnancies lead to a higher risk of adult onset diseases including hypertension, obesity, and metabolic syndrome. Covers pregnancy and pathologic pregnancy in detail.

SURGERY 976

The science of diabetes and obesity as it correlates to the clinical setting. The history of endocrinology and discovery of insulin will provide the basis for understanding hormonal mechanisms controlling fuel metabolism and how these processes become dysfunctional in different disease states. Topics will include pancreatic and extrapancreatic control of metabolism, and diseases linked with obesity, including PCOS, type 2 diabetes, and cancer. Lifestyle, medical, and surgical treatments of obesity and diabetes, including pharmacologic mechanisms of insulin and non-insulin diabetes therapeutics and bariatric surgery, will be highlighted. The public health perspective will shine light on societal factors that influence obesity and diabetes care. Provides an advanced scientific foundation with which to approach evidence-based care and treatment of individuals with obesity and/or diabetes.