TOXICOLOGY I

PHMSCI 432

Basic biochemistry as the biochemical basis for drug action. Focus on biopolymers (proteins, nucleic acids) as intended and unintended targets of current drug therapy and the major biochemical pathways in which they operate. Review of protein structure, enzymatic activity, metabolic pathways, membrane biochemistry, mechanism of drug action, DNA mutation and repair.

PHMSCI 558

Basic laboratory techniques employed in pharmacological and toxicological research.

COMPBIO 555

Science of toxicology as it relates to veterinary practice. The principles of toxicology and the mechanism and treatment of toxicants commonly encountered in small and large animals will be presented.

M&ENVTOX 800

Current research in environmental toxicology and pathology and other topics of interest and importance to environmental toxicologists.

M&ENVTOX/PATH/PHMCOL-M/PHMSCI/POPHLTH 626

Survey of the basic methods and fundamental biochemical mechanisms of toxicity. Toxicity in mammalian organ systems, techniques for evaluating toxicity, as well as mechanisms of species specificity, and environmental interactions (with toxicant examples) are presented.