DESIGN OF BIOLOGICAL MOLECULES

BME/CBE 560

Properties of biological molecules; enzyme kinetics, enzyme reactors, and enzyme engineering; metabolic engineering; microbial growth kinetics; bioreactor design; bioseparations.

BIOCHEM 719

Topics covered include protein structure and folding, protein dynamics, biological catalysis, membrane structure and assembly, nucleic acid structure and folding, and bioenergetics. Each topic includes discussion of the primary literature, hypothesis generation, experimental design, data, analysis and interpretation underlying the facts in the textbook. Supports transition from undergraduate consumers of knowledge to graduate students and future independent scientists who will discover and add new knowledge.

CBE 781

Protein engineering and protein-protein interactions, receptor-ligand binding, cell metabolism and signaling, metabolic engineering and synthetic biology, tissue engineering. Additional topics may be covered such as: regenerative medicine, biomaterials, microbe-host interactions.

BMOLCHEM 720

Covers following areas from historical to modern contexts: biochemistry of post-translational modification of proteins, model organisms, transcriptional switches, chromosome replication, and RNA in biological regulation.

BIOCHEM 207

Introduces the lab skills and techniques used in biochemistry and molecular biology laboratories. Engineer mutants of the T7 bacteriophage and test the virulence of the bacteriophages on various bacterial strains. Integrate biochemistry, molecular biology, microbiology, genetics, and basic laboratory techniques.