EARLY DRUG DISCOVERY

PHMSCI 786

Synthesis and biosynthesis of natural products in drug discovery. Topics include: natural products in drug discovery; biosynthetic pathways and synthetic strategies for major natural product classes; and basic bioorganic chemistry and enzyme mechanisms in biosynthesis.

PHMSCI 756

Provides a high-level overview of how data analysis techniques augment the drug discovery and development process. Focuses on project-based skills-building through the application of industry-standard software and use of public databases. Explores best practices for data processing and management to ensure experimental reproducibility. Develops troubleshooting skills through critical evaluation of data analysis results and root cause analysis.

PHMSCI 762

Overview of the drug development process from discovery to investigational new drug application (IND). Drug discovery (target identification, target validation, and hit-to-lead) preclinical CMC activities, and preclinical pharmacology, pharmacokinetic, and toxicology studies as they apply to both small and large molecule drugs.

PHMSCI 680

Learn about essential components of drug development and cutting-edge research in drug discovery, drug action, and drug delivery. Focus on useful and practical information and essential underpinnings in chemistry, biology, physical chemistry, and engineering.

PHMSCI 757

Scientific process of drug development from discovery through clinical trials. Brief history of drug development, along with an overview of drug discovery, preclinical, and clinical activities that take place during development. Application to real-world drug development scenarios and challenges, especially as they apply to development of drugs to treat neurological diseases.