REGULATION OF GENE EXPRESSION (ADVANCED SEMINAR)

BIOCHEM/GENETICS/MDGENET 620

Focuses on the basic molecular mechanisms that regulate DNA, RNA, and protein metabolism in eukaryotic organisms.

BIOCHEM/BMOLCHEM 913

Student-led discussions of RNA-related problems.

BIOCHEM/GENETICS/MICROBIO 612

Molecular basis of bacterial physiology and genetics with emphasis on molecular mechanisms; topics include nucleic acid-protein interactions, transcription, translation, replication, recombination, regulation of gene expression.

BIOCHEM/CHEM 945

Presentations and discussions of recently published research in chemical biology and related areas.

GENETICS 885

With the availability of genome sequences and high-throughput techniques, organismal physiology can now be examined on a global scale by monitoring the behavior of all genes or proteins in a single experiment. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course material will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proteomic screening methods, and protein-interaction network analysis. In addition to lecture time, the course includes computer lab where students get hands-on experience analyzing genomic and proteomic datasets. Students should have coursework in general statistics and intermediate or advanced genetics.