CNS DRUG DESIGNS, ACTIONS, AND APPLICATIONS I

PHMSCI 581

Provides an in-depth introduction to the molecular and cellular principles of pharmacology. Emphasis is on the mechanisms of drug and small molecule action in cells, with a particular focus on downstream signaling pathways, second messenger systems, protein kinase cascades, and the regulation of gene transcription.

PHMSCI 521

Pharmacological actions of important drugs, including drugs that affect the peripheral and central nervous systems.

PHARMACY 771

Gain additional understanding of how chemical features can influence the biological activity of a molecule on molecular targets within the central nervous system, how alteration of signaling through these targets occurs and leads to physiologically relevant changes, and how major classes of pharmaceuticals acting on the central nervous system are applied in healthcare settings to improve patient outcomes. Integration between concepts arising at the chemical, molecular, cellular, systems, organism, and societal levels will be explored.

PHMSCI 761

Introduction to basic concepts of drug delivery and action, methods used to study drug action. Includes a brief survey of drugs acting on the cardiovascular system, the central nervous system and other drug targets.

PHMSCI 757

Survey of the drug development process from target identification, development, preclinical studies, clinical trials to post-approval monitoring, particularly as applicable to neuroactive drugs. Differences between small and large molecules (biologics) will be covered, along with a basic coverage of regulatory authorities. A brief history of drug development will be provided, along with coverage of special topics related to stages of the drug development process. Broad survey-style overview of the phases in the drug development process, regulatory considerations, relevant vocabulary, and the ability to communicate within the industry.