The Molecular Basis of Hematologic Malignancies
Covers the molecular basis of hematologic malignancies, focusing on molecular assays, cytogenetics, and integrating molecular data with histology for diagnosis and therapy.
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Understanding molecular mechanisms of hematologic disease, and developing a foundation in the principles of relevant molecular assays, is critical to providing appropriate patient care. Topics include bases of neoplastic disorders of the hematopoietic and lymphoid systems, how underlying molecular abnormalities contribute to the pathophysiology of these diseases, and the evolving spectrum of molecular and cytogenetic/FISH testing and other ancillary testing (such as flow cytometry), which are often utilized in the work-up of hematopoietic and lymphoid malignancies. Learn about strengths and weaknesses of these technologies, and how pathologists integrate results of molecular testing with the traditional histologic exam to produce accurate diagnoses and drive clinical decision making. Develop an understanding of how knowing the underlying molecular pathology of a hematopoietic or lymphoid malignancy can inform prognosis and guide therapy.
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