Laboratory Medicine Customized

Laboratory Medicine Customized teaches basic science principles of common lab tests, applying them to clinical judgments and patient questions while customizing content to specialty interests.

offering recorded2 credits
Recorded instructors · Spring 2027 No instructors listed

Summary

What you’ll be able to do

  • Define and apply the concepts of sensitivity and specificity.

  • Define and apply negative and positive predictive value. Explain how these values are influenced by the prevalence (prior probability) of disease in defined populations (Bayes theorem).

  • Describe how reference intervals are derived and used and the different types of reference intervals including those derived from population distributions, from expert consensus recommendation, or from evidence-based determination of “threshold” values based on a test’s predictive value in a clinical algorithm.

  • Explain why 5% percent of laboratory test results from healthy individuals might fall outside a reference range.

  • Explain the concept of variability in repeated measurements, as well as variability within and between individuals.

  • Describe the contributors to analytical uncertainty (precision, accuracy, bias, coefficient of variation) and how the sources of variability relate to clinical interpretation of changes in test results.

  • Discuss the consequences of ordering unnecessary testing.

  • Explain the roles of preanalytical and postanalytical variables in affecting test results and thereby impacting patient care.

  • List common sources of preanalytical errors.

  • Describe the effects of blood-drawing technique on test results.

  • Compare and contrast the use of specimen tubes with various colored tops, as well as other specimen containers, and why they cannot be used interchangeably.

  • Describe the broad categories of situations that may result in test interference such as incomplete tube fill, hemolysis, lipemia, bilirubinemia, cross-reacting and interfering substances.

  • List some important limitations and pitfalls of common lab tests.

  • Explain the Choosing Wisely campaign. Present one Choosing Wisely recommendation in depth while explaining its components, rationale, evidence, and arguments for and against.

Source: UW Guide

Grade history

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Prerequisites

Course map

MED SC-M 810, 811, 812, and 813

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Professors

Spring 2027

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Calendar & sections

Spring 2027

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SectionModeEnrolled / capacityWaitlist
LEC 006Online Only0 / 00

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Student experience

the class

Learn the basic science principles of common laboratory tests. Apply this knowledge to assignments in which you make clinical judgments and answer common patient questions about lab test interpretations. Customize the curriculum based on your specialty interests.

difficulty & workload

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Topics

  • Basic science principles of common laboratory tests
  • Clinical judgment and patient communication regarding lab interpretations
  • Sensitivity and specificity
  • Predictive values and Bayes theorem
  • Reference intervals derivation and use
  • Analytical uncertainty and variability
  • Preanalytical and postanalytical variables
  • Choosing Wisely campaign and recommendations

Skills

  • Define and apply sensitivity and specificity
  • Apply predictive values using Bayes theorem
  • Interpret analytical uncertainty and variability
  • Explain preanalytical and postanalytical variables
  • Present a Choosing Wisely recommendation

Grades

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Sources & history

UW–Madison

Catalog & offerings

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Selected offering source records
PATH 922 · Spring 2027

Laboratory Medicine Customized

Recorded 2026-10-14
Raw records
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    "offering_id": "1274:704:026146",
    "course_id": "PATH 922",
    "course_uid": "course_3be960f6feed943784bd9835",
    "term_id": "1274",
    "source_course_id": "026146",
    "source_subject_id": "704",
    "title": "Laboratory Medicine Customized",
    "credits_min": 2,
    "credits_max": 2,
    "typically_offered": "Not Applicable"
  }
]
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Model outputs & technical records
Qwen/Qwen3.8-27B
LLM outputs across runs
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Model & dataset provenance
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