HUMAN FAMILY TREE

GENETICS/MDGENET 565

Principles, problems, and methods of modern human genetics. Focuses on how researchers discover the genetics of diseases and how those discoveries are used to improve clinical practice. Surveys aspects of (i) the molecular function of the human genome, (ii) the basic principles of human genetics including statistical genetics, quantitative genetics, and genomic variation in human populations, (iii) the genetics of rare disorders and common diseases, and genomic analysis approaches, including genome-wide association studies and sequencing, and (iv) how genetics are used in medicine and discussions covering ethical considerations of human genomic data.

MEDSC-M 810

Develop clinical knowledge and skills necessary to care for patients in Pediatrics and Obstetrics and Gynecology, with emphasis on unique skills such as taking care of vulnerable populations as identified in women's and child health and working with caregivers in addition to the patient themselves. Increase knowledge of fundamental science concepts introduced in Human Family Tree during Phase 1 of the curriculum, such as embryology and teratology, genetic testing, and neurodevelopment. Clinical experiences will occur in a range of representative inpatient, outpatient and surgical settings. In structured educational sessions, compare and contrast selected topics in pediatric, obstetric, and gynecologic patient populations, highlighting the relevant physiology, pathophysiology, basic science, and public health topics.

OBS&GYN 710

A broad grounding in reproductive endocrine physiology at the graduate level, with an emphasis on human and human reproductive health wherever possible. Encompasses an overview of fundamental concepts in endocrinology, the hypothalamic-pituitary axis, steroidogenesis, early embryonic development, pregnancy and maternal-fetal adaptations, and pathologies associated with endocrine disruption and dysregulation. Provides more focus on pathologic pregnancies because such pregnancies lead to a higher risk of adult onset diseases including hypertension, obesity, and metabolic syndrome. Covers pregnancy and pathologic pregnancy in detail.

PATH 949

The genome impacts human health and disease from the moment of conception throughout growth, development, and aging. This course offers a comprehensive overview of clinical laboratory testing in the fields of medical genetics and public health. Topics include how genetic testing is integrated into patient care, including prenatal genetics, newborn screening, genetic testing in children and adults, and oncology genetics. Students will develop a strong foundational knowledge of basic genetics principles, identify indications for genetic testing, interpret population screening results and the implications for public health, assess the utility of diagnostic testing, and recognize the limitations of genetic testing and clinical laboratory medicine. It is anticipated that students will incorporate these concepts, knowledge, experiences, and evidence in their future clinical practice.

GENECSLR 742

Review human development (normal and abnormal) and the influence of genetic disorders and teratogens, common indications for prenatal genetic counseling as well as available prenatal diagnosis and screening techniques. Prepares the genetic counseling student for the prenatal clinical practicum.