{"schema_version":1,"url":"https://uwcourses.com/courses/GENETICS_NEURODPT_650","title":"GENETICS/NEURODPT 650: Functional Genomics of Brain Disorders | UW–Madison","dataset":{"revision":"e243353dcb7d79b7247ced91d69443ef4c2a6349","repository":"twangodev/uwcourses","schema_version":6,"importer_version":"7","projection_id":"52a78527ff09011d88cb04c7d43867d9fbfec2930bf1dd2ec359ebd2844e0b07","observed_at":"2026-09-07T15:55:43.033547+00:00","built_at":"2026-09-10T19:50:42.743001+00:00","courses":8951,"current_instructors":5754,"limited":false,"terms":["1272","1264","1262","1254","1252","1244","1242","1234","1232","1224","1222","1212","1204","1202","1194","1192","1184","1182","1174","1172","1164","1162","1154","1152","1144","1142","1134","1132","1124","1122","1114","1112","1104","1102","1094","1092","1084","1082","1074","1072"],"term":"1272","departments":[{"subject":"AAE","count":90},{"subject":"ABT","count":20},{"subject":"ACCTIS","count":36},{"subject":"ACTSCI","count":14},{"subject":"AFAERO","count":10},{"subject":"AFRICAN","count":87},{"subject":"AFROAMER","count":71},{"subject":"AGROECOL","count":21},{"subject":"AMERIND","count":53},{"subject":"ANAT&PHY","count":7},{"subject":"ANATOMY","count":2},{"subject":"ANESTHES","count":8},{"subject":"ANSCI","count":57},{"subject":"ANTHRO","count":95},{"subject":"ART","count":125},{"subject":"ARTED","count":10},{"subject":"ARTHIST","count":121},{"subject":"ASIALANG","count":129},{"subject":"ASIAN","count":109},{"subject":"ASIANAM","count":28},{"subject":"ASTRON","count":38},{"subject":"ATMOCN","count":69},{"subject":"BIOCHEM","count":51},{"subject":"BIOCORE","count":10},{"subject":"BIOLOGY","count":14},{"subject":"BIOMDSCI","count":18},{"subject":"BME","count":66},{"subject":"BMI","count":41},{"subject":"BMOLCHEM","count":10},{"subject":"BOTANY","count":69},{"subject":"BSE","count":44},{"subject":"C&ESOC","count":73},{"subject":"CBE","count":48},{"subject":"CHEM","count":101},{"subject":"CHICLA","count":52},{"subject":"CIVENGR","count":133},{"subject":"CLASSICS","count":47},{"subject":"CNP","count":10},{"subject":"CNSRSCI","count":50},{"subject":"COMARTS","count":137},{"subject":"COMPBIO","count":15},{"subject":"COMPLIT","count":11},{"subject":"COMPSCI","count":138},{"subject":"COUNPSY","count":78},{"subject":"CRB","count":19},{"subject":"CS&D","count":71},{"subject":"CSCS","count":40},{"subject":"CURRIC","count":193},{"subject":"DANCE","count":93},{"subject":"DERM","count":8},{"subject":"DS","count":88},{"subject":"DYSCI","count":35},{"subject":"ECE","count":155},{"subject":"ECON","count":145},{"subject":"EDPOL","count":114},{"subject":"EDPSYCH","count":97},{"subject":"ELPA","count":70},{"subject":"EMA","count":53},{"subject":"EMERMED","count":17},{"subject":"ENGL","count":206},{"subject":"ENTOM","count":40},{"subject":"ENVIRST","count":148},{"subject":"EP","count":15},{"subject":"EPD","count":67},{"subject":"ESL","count":16},{"subject":"F&WECOL","count":60},{"subject":"FAMMED","count":22},{"subject":"FINANCE","count":50},{"subject":"FOLKLORE","count":40},{"subject":"FOODSCI","count":43},{"subject":"FRENCH","count":63},{"subject":"GEN&WS","count":145},{"subject":"GENBUS","count":72},{"subject":"GENECSLR","count":17},{"subject":"GENETICS","count":60},{"subject":"GEOG","count":113},{"subject":"GEOSCI","count":83},{"subject":"GERMAN","count":82},{"subject":"GLE","count":48},{"subject":"GNS","count":38},{"subject":"GREEK","count":27},{"subject":"HDFS","count":41},{"subject":"HEBR-BIB","count":13},{"subject":"HEBR-MOD","count":10},{"subject":"HISTORY","count":233},{"subject":"HISTSCI","count":56},{"subject":"HONCOL","count":13},{"subject":"ILS","count":43},{"subject":"INFOSYS","count":9},{"subject":"INTEGART","count":7},{"subject":"INTEGSCI","count":22},{"subject":"INTER-AG","count":18},{"subject":"INTER-HE","count":11},{"subject":"INTER-LS","count":22},{"subject":"INTEREGR","count":16},{"subject":"INTLBUS","count":21},{"subject":"INTLST","count":50},{"subject":"ISYE","count":83},{"subject":"ITALIAN","count":53},{"subject":"JEWISH","count":56},{"subject":"JOURN","count":88},{"subject":"KINES","count":128},{"subject":"LACIS","count":26},{"subject":"LANDARC","count":61},{"subject":"LATIN","count":24},{"subject":"LAW","count":120},{"subject":"LEGALST","count":48},{"subject":"LINGUIS","count":35},{"subject":"LIS","count":89},{"subject":"LITTRANS","count":78},{"subject":"LSC","count":52},{"subject":"M&ENVTOX","count":7},{"subject":"MARKETNG","count":62},{"subject":"MATH","count":153},{"subject":"MDGENET","count":8},{"subject":"ME","count":130},{"subject":"MEDHIST","count":43},{"subject":"MEDICINE","count":60},{"subject":"MEDIEVAL","count":32},{"subject":"MEDPHYS","count":39},{"subject":"MEDSC-M","count":29},{"subject":"MEDSC-V","count":41},{"subject":"MHR","count":68},{"subject":"MICROBIO","count":45},{"subject":"MILSCI","count":16},{"subject":"MM&I","count":22},{"subject":"MOLBIOL","count":6},{"subject":"MS&E","count":59},{"subject":"MUSIC","count":165},{"subject":"MUSPERF","count":126},{"subject":"NAVSCI","count":20},{"subject":"NE","count":44},{"subject":"NEURODPT","count":11},{"subject":"NEUROL","count":7},{"subject":"NEURSURG","count":4},{"subject":"NTP","count":11},{"subject":"NURSING","count":111},{"subject":"NUTRSCI","count":65},{"subject":"OBS&GYN","count":18},{"subject":"OCCTHER","count":39},{"subject":"ONCOLOGY","count":14},{"subject":"OPHTHALM","count":5},{"subject":"OTM","count":43},{"subject":"PATH","count":34},{"subject":"PATH-BIO","count":29},{"subject":"PEDIAT","count":26},{"subject":"PHARMACY","count":31},{"subject":"PHILOS","count":77},{"subject":"PHMCOL-M","count":11},{"subject":"PHMPRAC","count":45},{"subject":"PHMSCI","count":60},{"subject":"PHYASST","count":37},{"subject":"PHYSICS","count":88},{"subject":"PHYSIOL","count":3},{"subject":"PHYTHER","count":37},{"subject":"PLANTSCI","count":52},{"subject":"PLPATH","count":35},{"subject":"POLISCI","count":192},{"subject":"POPHLTH","count":58},{"subject":"PORTUG","count":33},{"subject":"PSYCH","count":101},{"subject":"PSYCHIAT","count":22},{"subject":"PUBAFFR","count":54},{"subject":"PUBLHLTH","count":23},{"subject":"RADIOL","count":11},{"subject":"REALEST","count":41},{"subject":"RELIGST","count":90},{"subject":"RHABMED","count":9},{"subject":"RMI","count":24},{"subject":"RP&SE","count":102},{"subject":"S&APHM","count":17},{"subject":"SCANDST","count":73},{"subject":"SLAVIC","count":89},{"subject":"SOC","count":149},{"subject":"SOCWORK","count":87},{"subject":"SOILSCI","count":46},{"subject":"SPANISH","count":83},{"subject":"SRMED","count":21},{"subject":"STAT","count":94},{"subject":"STDYABRD","count":52},{"subject":"STS","count":8},{"subject":"SURGERY","count":25},{"subject":"SURGSCI","count":33},{"subject":"THEATRE","count":91},{"subject":"URBRPL","count":60},{"subject":"UROLOGY","count":5},{"subject":"ZOOLOGY","count":89}],"deployed_at":null},"data":{"course":{"run_id":"20260907T155543-ce3781c4","semester":"1272","observed_at":"2026-09-07 15:55:43.033547+00:00","record_version_id":"17fd60b97823ec7ab98aadb252bf8f2eb0726225d6db0a2b2b2532b7d92044ad","course_id":"GENETICS/NEURODPT 650","course_uid":"course_cebdf4520607b8c5274a4058","catalog_version_id":"bcb574e0b7a3f6d609fb3cd983c82e4571cc36d39db5d78be24cf06c21b373e7","course_number":650,"subjects":["GENETICS","NEURODPT"],"title":"FUNCTIONAL GENOMICS OF BRAIN DISORDERS","description":"Functional genomics methods (RNA-seq, ATAC-seq, Hi-C, ChIP-seq, Tag, etc.) and their applications in the study of molecular and cellular mechanisms governing brain development, evolution, and neurodevelopmental and neuropsychiatric disorders. Overview of relevant aspects of Genetics and Neuroscience, including genomic approaches for gene discovery for human disorders and key properties of brain cells and circuit development. Bioinformatic approaches for analyzing genome-scale data sets. Critical consideration of experimental design and analysis strategies through reading and discussion of primary research literature and the development of an original research proposal. Emphasis will be placed upon how to effectively communicate science (written and oral).","requirements_text":"GENETICS 466,468,BIOCORE 383,PSYCH/​ZOOLOGY  523, or graduate/professional standing","credits_min":null,"credits_max":null,"credit_offering_ids":[],"llm_job_id":"enrich-8b774950c2b6adfdc46d1b82","llm_output_id":"b043e3245e6be9d885532756434a4fe67033d997392f49c8a506c267ee4c7fa4","llm_model":"nvidia/Qwen3.6-35B-A3B-NVFP4","llm_model_revision":"1355db6a052410cfd62085d94b58866fd0f2c3c5","llm_task_version":"14","llm_search_status":"valid","llm_summary":"This course covers functional genomics methods and their applications in studying brain development and neurodevelopmental disorders.","llm_topics":["Functional genomics methods (RNA-seq, ATAC-seq, Hi-C, ChIP-seq, Tag).","Molecular and cellular mechanisms of brain development and disorders.","Genomic approaches for gene discovery.","Properties of brain cells and circuit development.","Bioinformatic analysis of genome-scale data.","Primary research literature analysis."],"llm_skills":["Bioinformatic analysis of genome-scale data.","Experimental design and analysis strategy formulation.","Scientific communication and research proposal development."],"llm_assumed_background":["Principles of genetics, general genetics, cellular biology, and neurobiology.","Foundational knowledge in cellular biology, transmission and molecular genetics, population genetics, and cellular neurophysiology."],"llm_search_phrases":["functional genomics brain disorders","RNA-seq ATAC-seq ChIP-seq","neurodevelopmental disorders genomics","bioinformatics genome-scale data","brain development evolution genomics"],"llm_requirements_status":"valid","llm_student_summary_status":"valid","llm_experience_status":"insufficient_evidence","catalog_variants":[],"student_summary":{"context_hash":"5c930149949d38ba961242ea758e5778956b3e22c70d99a6c1e8c88cdf2ac0a0","course_id":"GENETICS/NEURODPT 650","current_instructors":[],"difficulty_workload":[],"errors":[],"historical_context":[],"message":"No course-specific reviews available","offered":false,"profile_hash":"5cb4dabf887cdbcd8c00d5a1312e10828b95c63f30bc3ea76aea199565390d02","quick_take":[{"citations":[{"course_id":"GENETICS/NEURODPT 650","run_id":"20260907T155543-ce3781c4","source_record":{"entity_id":"d6017114-4f90-35f4-9a6c-92c4ed2d1436","file":"tables/observations.parquet","kind":"grades","source":"madgrades"},"table":"grades_latest","term_id":"1264","type":"grade"}],"text":"Recent recorded grades — Spring 2026: 3.71 GPA, 100.0% A/AB (n=7 letter grades)."}],"student_experience":[],"task_hash":"74fb0997943e888960bbc9e47db8c4fd12e4292d55c20509d8d89db6a9910f68","teaching_history":[],"term_id":"1272","term_name":"2026 Fall","version":2},"requirements":{"nodes":[{"children":["n1","n2","n3","n4","n5"],"condition":null,"course":null,"evidence":"GENETICS 466,468,BIOCORE 383,PSYCH/ZOOLOGY 523, or graduate/professional standing","id":"n0","kind":"any"},{"children":[],"condition":null,"course":{"course_number":466,"minimum_grade":null,"subjects":["GENETICS"],"timing":"prior"},"evidence":"GENETICS 466","id":"n1","kind":"course"},{"children":[],"condition":null,"course":{"course_number":468,"minimum_grade":null,"subjects":["GENETICS"],"timing":"prior"},"evidence":"468","id":"n2","kind":"course"},{"children":[],"condition":null,"course":{"course_number":383,"minimum_grade":null,"subjects":["BIOCORE"],"timing":"prior"},"evidence":"BIOCORE 383","id":"n3","kind":"course"},{"children":[],"condition":null,"course":{"course_number":523,"minimum_grade":null,"subjects":["PSYCH","ZOOLOGY"],"timing":"prior"},"evidence":"PSYCH/ZOOLOGY 523","id":"n4","kind":"course"},{"children":[],"condition":"graduate/professional standing","course":null,"evidence":"graduate/professional standing","id":"n5","kind":"condition"}],"notes":[],"root":"n0","status":"parsed"},"instructors":[],"offerings":[],"sections":[],"grade_instructors":[{"instructor_uid":"instructor_6da50b5852d326f3066964ba","source":"madgrades","source_instructor_id":"6317734","identity_basis":"source_id","identity_status":"source_identified","name":"ANDRE MOURA DA COSTA E SOUSA","email":null,"first_observed_at":"2026-09-06 23:14:58.172943+00:00","last_observed_at":"2026-09-07 15:55:43.033547+00:00","grade_statistics":{"gpa":3.76,"graded":52,"counts":[35,9,8,0,0,0,0],"sections":42},"instructor_url":"/instructors/ANDRE_MOURA_DA_COSTA_E_SOUSA--instructor_6da50b5852d326f3066964ba"},{"instructor_uid":"instructor_a65313e1cd0f224501485ce3","source":"madgrades","source_instructor_id":"3728293","identity_basis":"source_id","identity_status":"source_identified","name":"DONNA WERLING","email":null,"first_observed_at":"2026-09-06 23:14:58.172943+00:00","last_observed_at":"2026-09-07 15:55:43.033547+00:00","ratings":{"review_count":1,"quality":5,"difficulty":4,"quality_count":1,"difficulty_count":1,"profile_id":"rmp:3061483","source_url":"https://www.ratemyprofessors.com/professor/3061483","match_basis":"exact_name","observed_at":"2026-09-07 16:43:16.727715+00:00","courses":{"course_3072ef2bc2ee7e4a222f0281":{"review_count":1,"quality":5,"difficulty":4,"quality_count":1,"difficulty_count":1}},"bayesian_quality":3.7235102700443767,"prior_mean":3.6596857835465957,"prior_weight":20},"grade_statistics":{"gpa":3.412,"graded":370,"counts":[137,107,77,26,21,2,0],"sections":50},"instructor_url":"/instructors/DONNA_WERLING--instructor_a65313e1cd0f224501485ce3"}],"grades":[{"run_id":"20260907T155543-ce3781c4","semester":"1272","observed_at":"2026-09-07 15:55:43.033547+00:00","course_id":"GENETICS/NEURODPT 650","course_uid":"course_cebdf4520607b8c5274a4058","term_id":"1264","term_name":"Spring 2026","instructors":["Andre Moura Da Costa E Sousa","Donna Werling"],"a":3,"ab":4,"b":0,"bc":0,"c":0,"d":0,"f":0,"satisfactory":0,"unsatisfactory":0,"credit":0,"no_credit":0,"passed":0,"incomplete":0,"no_work":0,"not_reported":0,"other":0,"total":7,"source_aliases":["GENETICS/NEURODPT 650"]}],"statistics":{"gpa":3.714,"graded":7,"counts":[3,4,0,0,0,0,0]},"grade_conflicts":[],"evidence":{"history":["/data/e243353dcb7d79b7247ced91d69443ef4c2a6349/history/course_cebdf4520607b8c5274a4058-0.json"],"traces":["/data/e243353dcb7d79b7247ced91d69443ef4c2a6349/traces/course_cebdf4520607b8c5274a4058-0.json"],"results":["/data/e243353dcb7d79b7247ced91d69443ef4c2a6349/results/course_cebdf4520607b8c5274a4058-0.json"]},"revision":"e243353dcb7d79b7247ced91d69443ef4c2a6349"},"context":{"all":{"term":"","gpa":3.7142857142857144,"count":7,"university":null,"departments":[{"subject":"GENETICS","comparison":null},{"subject":"NEURODPT","comparison":null}]},"terms":{"1264":{"term":"1264","gpa":3.7142857142857144,"count":7,"university":null,"departments":[{"subject":"GENETICS","comparison":null},{"subject":"NEURODPT","comparison":null}]}},"benchmarks":{"all":{"school":{"size":1283,"gpa":3.6229729166451925,"topShare":80.13669149396227,"count":66},"GENETICS":null,"NEURODPT":null},"terms":{"1264":{"school":{"size":1283,"gpa":3.6229729166451925,"topShare":80.13669149396227,"count":66},"GENETICS":null,"NEURODPT":null}}}},"instructorTrends":[{"uid":"instructor_6da50b5852d326f3066964ba","name":"ANDRE MOURA DA COSTA E SOUSA","count":7,"terms":[{"term":"1264","count":7,"sections":1,"gpa":3.7142857142857144}]},{"uid":"instructor_a65313e1cd0f224501485ce3","name":"DONNA WERLING","count":7,"terms":[{"term":"1264","count":7,"sections":1,"gpa":3.7142857142857144}]}],"following":[],"projection":null}}