DEVELOPMENTAL GENETICS

GENETICS/MDGENET 707

A research-level analysis of the current status of the investigation of processes controlling differential gene activity and cellular behavior. The major emphasis is genetic. In successive years, the focus moves from the gene to the cell to the organism.

CRB 650

Covers the most current knowledge of the principles of organogenesis. Focuses on the molecular and cellular pathways leading to normal tissue and organ development and regeneration, including in depth discussions of specification and differentiation processes.

ZOOLOGY 470

Introduction to the major features and mechanisms of early embryonic development in animals, including (1) the major stages of early development, (2) how form arises in the embryo (morphogenesis), (3) how differences arise between cells in the embryo, and (4) how specific genes control these processes.

GENETICS 627

Advanced genetics course focusing on genetic mechanisms of animal embryonic development, with particular emphasis on central molecular circuitries that control development and genetic analytical tools used to reveal them. Address topics including maternal and epigenetic inheritance, the egg-to-embryo transition, pattern formation, organogenesis, coordination of cellular and molecular mechanisms, and animal models of human congenital disorders.

CRB 810

Clinically relevant methods of scientific thought, inquiry and analysis via the presentation of specific research topics. Emerging concepts in developmental genetics and embryonic stem (ES) cell biology are used as a means of introducing the participants to the critical importance of identifying the "right" question, selecting the "best" tools to answer the question, using the appropriate logic to interpret experimental results and finally, constructing appropriate conclusions. Application of the literature of mouse genetics and laboratory research to biomedical health decisions. Strong emphasis on the tools used in the research literature and to 'get your hands dirty' learning the basics of the laboratory techniques involved.