GENOMIC SCIENCE

GENETICS 885

With the availability of genome sequences and high-throughput techniques, organismal physiology can now be examined on a global scale by monitoring the behavior of all genes or proteins in a single experiment. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course material will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proteomic screening methods, and protein-interaction network analysis. In addition to lecture time, the course includes computer lab where students get hands-on experience analyzing genomic and proteomic datasets. Students should have coursework in general statistics and intermediate or advanced genetics.

GENETICS 548

Profound advances are now possible thanks to genomic data and analysis. Introduces the structure, function, and evolution of genomes. It also outlines the realized and prospective benefits of genomic technology for human health, agriculture, and conservation.

ANSCI 366

Genomics has revolutionized many fields of science, including animal breeding, plant breeding, physiology, microbiology, and human medicine. A basic overview of the latest concepts in genomics, including 3D genome organization, the importance of genome annotation, the use of genomic testing in plant and animal breeding, the potential of genomic prediction on human medicine, and the latest advances in omics integration.

CHEM 923

Cross-disciplinary exposure to cutting edge research in genomic sciences. Seminars presented by trainees and other scientists who study genomics using approaches based in chemistry, computer science, biostatistics, engineering and biological and biomedical sciences. Research objectives, findings and future directions are discussed.

GENETICS 564

The basic principles of genomics, proteomics and bioinformatics will be taught through a semester-long project of the students choosing. Creative problem solving in science skills will be learned through a variety of active-learning techniques that include: reading of primary literature, group presentations, peer review, bioinformatic lab exercises, science communication skills (writing visualization), and creating a website. Emphasis will be placed upon how to effectively communicate science (written, oral and written). Topics include: genomic sequencing, phylogeny, domain analysis, transcriptomics, CRISPR screens, chemical genomics, quantitative proteomics and protein networks. Capstone course.