Protein and Enzyme Structure and Function
Advanced study of protein structure, dynamics, folding, and enzymatic catalysis, including kinetics, reaction mechanisms, and structural methods like X-ray crystallography.
Summary
Recent recorded grades — Fall 2023: 3.37 GPA, 52.2% A/AB (n=23 letter grades); Fall 2024: 3.28 GPA, 52.2% A/AB (n=23 letter grades); Fall 2025: 3.93 GPA, 95.5% A/AB (n=22 letter grades).
What you’ll be able to do
Identify basic stereochemical principles of protein components
Describe the chemistry of amino acids
Describe the noncovalent forces that control the secondary and tertiary structure of proteins
Evaluate the fundamental strengths and weaknesses of structures determined by X- ray crystallography and electron microscopy
Explain chemical kinetics as they apply to enzymes
Differentiate the role of cofactors in enzyme chemistry
Explain the fundamental underpinnings of protein stability, protein evolution, and their application to protein engineering by site-directed mutagenesis
Distinguish the key features of representative enzymes families including the ATPases and the peptidases
Compare the differences and unique properties of membrane proteins
Critically evaluate the primary biochemical literature regarding protein structure, function, and enzyme catalysis
Source: UW Guide
Grade history
↗All recorded terms · compare terms & instructors
Prerequisites
Course mapCHEM 345 and (BIOCHEM 501 or 507) or graduate/professional standing
- CHEM 345
- take one
- graduate/professional standing
This is a best-effort interpretation; check the catalog requirements above.
Prerequisite text tree
- Any of
- All of
- graduate/professional standing
Professors
Spring 2027No instructors recorded for this selection.
Historical instructors & teaching patterns
Recorded history may be incomplete and does not establish a future schedule.
Calendar & sections
Spring 2027Schedule loads here as you scroll.
| Section | Mode | Enrolled / capacity | Waitlist |
|---|
Times are Central. Select a meeting for details; export includes recorded dates for the selected sections.
Meeting source records
Student experience
the class
Recent recorded grades — Fall 2023: 3.37 GPA, 52.2% A/AB (n=23 letter grades); Fall 2024: 3.28 GPA, 52.2% A/AB (n=23 letter grades); Fall 2025: 3.93 GPA, 95.5% A/AB (n=22 letter grades).
difficulty & workload
No workload feedback recorded.
Topics
- Protein structure, dynamics, and folding
- Physical organic chemistry of enzymatic catalysis
- Enzyme kinetics and receptor-ligand interactions
- Enzymatic reaction mechanisms
- Membrane proteins
- Representative enzyme families (ATPases, peptidases)
Skills
- Evaluate structural data from X-ray crystallography and electron microscopy
- Explain chemical kinetics in the context of enzymes
- Apply principles of protein stability and evolution to site-directed mutagenesis
- Critically evaluate primary biochemical literature on protein structure and enzyme catalysis
Grades
Latest available · Fall 2025— not enough history to project Spring 2027.
Grade distribution · % of letter grades
Grades over time
Through Fall 2025
More grade details Grade mix, volume & source data
Not enough comparable courses for Spring 2027 in UW–Madison.
Sources & history
Catalog & offerings
Descriptions, prerequisites, and recorded course offerings.
Catalog observation history
Observations at scan time; dates do not imply when a catalog change took effect.
Selected offering source records
No offering records for the selected term.
Raw records
[]
Student reviews
Original comments behind the course and instructor summaries.
Read original reviews
No records available.
Grade history
Recorded grade distributions by term, section, and instructor.
Explore recorded gradesRecorded 2026-10-14
Model outputs & technical records
LLM outputs across runs
Full model traces
Recorded model configuration, reasoning, and tool conversations.
Model & dataset provenance
{
"model": "Qwen/Qwen3.8-27B",
"model_revision": "1d4bf0f2ff6012fd82039f2fa52739d0dd7c60c0",
"task_version": "17",
"output_id": "a5eca38f03b977b629a36a1fb2f3f77a1d6b64e6413b1996334ca81fc9d9fe64",
"requirements_status": "valid",
"dataset_revision": "fc1811fa52e581ea57a35c0cf3343f8740a8ffbf",
"observed_at": "2026-10-14 17:50:09.728220+00:00"
}