CONCEPTS IN GENOMICS

GENETICS 234

The sequencing of genomes has transformed our understanding of the evolution of species and human history, our approaches to improve health and medicine, as well as how we tackle global environmental challenges. Explore the many ways in which the sequencing of genomes is revolutionizing our world, and dive into DNA from viral to human genomes. Understand how genomes are expressed, the impact on phenotype, as well as how it can change over time and in different conditions, are processes that are essential for life and the evolution of species.

GENETICS 885

With the availability of genome sequences and high-throughput techniques, organismal physiology can now be examined on a global scale by monitoring the behavior of all genes or proteins in a single experiment. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course material will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proteomic screening methods, and protein-interaction network analysis. In addition to lecture time, the course includes computer lab where students get hands-on experience analyzing genomic and proteomic datasets. Students should have coursework in general statistics and intermediate or advanced genetics.

GENETICS 548

Profound advances are now possible thanks to genomic data and analysis. Introduces the structure, function, and evolution of genomes. It also outlines the realized and prospective benefits of genomic technology for human health, agriculture, and conservation.

GENETICS 564

The basic principles of genomics, proteomics and bioinformatics will be taught through a semester-long project of the students choosing. Creative problem solving in science skills will be learned through a variety of active-learning techniques that include: reading of primary literature, group presentations, peer review, bioinformatic lab exercises, science communication skills (writing visualization), and creating a website. Emphasis will be placed upon how to effectively communicate science (written, oral and written). Topics include: genomic sequencing, phylogeny, domain analysis, transcriptomics, CRISPR screens, chemical genomics, quantitative proteomics and protein networks. Capstone course.

CHEM/GENETICS 626

Brings cutting-edge topics in the genomic sciences into the reach of those in chemistry, biology, engineering, computer science statistics fields. Enables biologically-oriented students to deal with advances in analytical science so that they may incorporate new genomic science concepts into their own scientific repertoires.